Isaac's Craft Kitchen & Brewery - Greenfield

Isaac's Craft Kitchen & Brewery - Greenfield

565 Greenfield Rd, Lancaster, PA 17601, United States

+1 717-393-6067

Restaurant, American restaurant, Brewery, Brewpub, Sandwich shop, Soup restaurant
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About This Place

Isaac's Craft Kitchen & Brewery in Greenfield, Lancaster, is a vibrant destination for those craving classic American fare elevated with a creative, craft-inspired twist. Nestled conveniently at 565 Greenfield Rd, this restaurant-brewpub hybrid offers an inviting atmosphere where the warmth of friendly service meets the buzz of a lively taproom experience.

The culinary offerings at Isaac's are a delightful mix of hearty sandwiches, comforting soups, and innovative brewery creations. The menu shines with standout dishes like the Bacon BBQ Flamebroiled Burger, which bursts with smoky richness from two slices of smoked bacon and a bold BBQ sauce, all nestled in a soft pretzel roll. For lovers of classic deli flavors, the Reuben Sandwich with its perfect balance of tender corned beef and tangy sauerkraut is a must-try. Soups here are not just sides but showstoppers—the Pepperjack Tomato Soup and the indulgent Clam Cheddar Cheese Soup offer layers of creamy, spicy comfort that have garnered loyal fans.

Isaac's attention to detail extends beyond mains: their Cheese Curds served with marinara sauce provide a crispy, golden crunch that perfectly complements a refreshing craft beer flight. Guests frequently rave about the bartending expertise of CeCe, who turns beer tasting into an immersive experience by demystifying the taproom’s diverse brews—from cold ales to the rich Toucan Brownie Nest stout. Many patrons find their palate thrilled by “that one beer” that strikes the perfect balance between flavor and freshness, so much so that they happily take crowlers home.

For families, Isaac’s excels in creating a welcoming environment. The kids menu is a charming standout, featuring playful options like a PB&J with rainbow bread and marshmallows, paired thoughtfully with healthy sides such as applesauce or fresh carrots, making mealtime fun and nutritious. Meanwhile, adults can enjoy creative combos like the Finch Combo with oven-roasted turkey and melted muenster on marbled pumpernickel, harmonizing comfort and flair in every bite.

The ambiance strikes a cozy, modern balance—the original Isaac’s signage and bright flamingos may be memories of yesteryear, but the current Greenfield location crafts a fresh vibe that blends upbeat energy with casual comfort. This is a place where locals and visitors alike can savor decadent dishes like the Chocolate Peanut Butter Pie or the Three Cheese Flatbread with Pesto, while soaking in the inviting atmosphere and attentive service that elevates the overall experience.

Whether you’re stopping in for a laid-back brew with your partner or bringing the entire family for a full dining adventure, Isaac's Craft Kitchen & Brewery delivers an authentically flavorful taste of Lancaster’s vibrant food scene. Expect generous portions, innovative menu items, and a staff eager to make every visit memorable.

Service options
Outdoor seating -contact delivery Delivery Takeaway Dine-in
Highlights
Fast service Great beer selection Great dessert
Popular for
Lunch Dinner Solo dining
Accessibility
Wheelchair-accessible car park Wheelchair-accessible entrance Wheelchair-accessible seating Wheelchair-accessible toilet
Offerings
Alcohol Beer Cocktails Coffee Comfort food Happy-hour drinks Happy-hour food Healthy options Quick bite Small plates Spirits Vegan options Vegetarian options Wine
Dining options
Lunch Dinner Catering Dessert Seating Table service
Amenities
Bar on site Toilet Wi-Fi Wi-Fi
Atmosphere
Casual Cosy
Crowd
Family friendly Groups Tourists
Payments
Credit cards Debit cards NFC mobile payments Credit cards
Children
Good for kids High chairs Kids' menu
Parking
Free of charge street parking Free parking lot Parking

Opening Hours

  • Monday
    11:00 AM - 09:00 PM
  • Tuesday
    11:00 AM - 09:00 PM
  • Wednesday
    11:00 AM - 09:00 PM
  • Thursday
    11:00 AM - 09:00 PM
  • Friday
    11:00 AM - 09:00 PM
  • Saturday
    11:00 AM - 09:00 PM
  • Sunday
    11:00 AM - 08:00 PM

Map & Directions

Visitor Reviews

  • April Zook
    3 week ago

    First I must start my review with the BEST bartender we’ve ever had, Ms. CeCe! What warm welcome she gave us! And she explained all the beer items that seemed a little mysterious to us. But talk is one thing so we tried the beers. All but one amazing beer didn’t suit our palate, a bit heavy and sweet, but that one beer, wow! We took two crowlers home! #1 on the menu, right where it belongs, German Pilsner Hartman’s Hero is clean, flavorful and refreshing. One could end with it being the last flavor, no chasing with a chip required. Truly impressive! We thought we’d found our lifetime favorite beer at another brewery but this ONE tops them all. Bravo Isaac’s brewer. You have done it! Amazing! Now to speak in the food… I was licking my bowl clean of the spicy tomato soup and wished I’d ordered a bowl instead of a cup, wow! Hubby got the Reuben sandwich with fries. Perfection! So clean. Outside dining that is lovely. We will return again and again! PS if you’re a guest at the attached Hotel, Isaac’s will offer you a discount.

  • Allison Shafer
    1 month ago

    The kids menu was a hit! Two kids in our group ordered the PB&J, which came with rainbow bread and marshmallows! They both loved it! I liked the fact that we could get healthy sides for the kids, like applesauce or carrots, instead of chips. I had a veggie wrap that I enjoyed. The prices were reasonable, I recommend this place for families!

  • Jon Morren
    4 month ago

    Enjoyed a couple of good brews and some appetizers with my wife this afternoon. We were in the taproom. The atmosphere was quite inviting. Our bartender CeCe was very helpful and attentive. We enjoyed the cheese curds and fried pickles which were both appropriately crispy and well seasoned. The cheese curds were served with a marinara sauce and the fried pickles were served with a horseradish mayo. Isaac's has definitely started to change it's image as a sandwich shop. Definitely worth checking this one out.

  • Marlene Black
    4 month ago

    Went to Lancaster to visit family and when our granddaughter suggested Isaac's, we were all in! I miss the Isaac's we used to eat at in Hummelstown. This Isaac's was closed for renovations,which included a brewery to open some time in April. I miss the decor of the original Isaac's with all the bright colors and flamingos and pretty birds. Also the fish tank is now gone. I guess this decor is the sign of the times, but it appeared so sterile. Our sandwiches were still pretty much the same with a few exceptions that have changed. I ordered my favorite Dr Browns creme soda, which they hadn't received in yet and some of their dessert menu was also not available. There appears to be outdoor seating once weather gets warmer.Service was slow this visit. But all in all, there is an Isaac's close by when we get to Lancaster.

  • Pam
    4 month ago

    I had the clam cheddar cheese soup and he had the pepper jack tomato bisque soup. Both were delicious. I had a half whooping crane sandwich (turkey on pretzel bun)and he had the half Salty Eagle (ham on pretzel bun). While the sandwiches were fine, The soups are the real stars. They also gave us a pickle appetizer. The waitress was great. The food is a little overpriced but the soup is worth it.

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